ตรวจหาความเสี่ยงโรคมะเร็งด้วยวิธี Preventive Genetic testing เพื่อการรักษาตั้งแต่แรกเริ่ม

Because we cannot prevent cancer 100%, what we can do is detect cancer at an early stage. Although there are currently health screening programs, including early cancer detection, it is still found that only certain types of cancer, such as breast cancer or cervical cancer, are detected early. Meanwhile, most patients with other types of cancer still receive treatment at stages 3 – 4, which have a lower chance of complete recovery.
<h2 style="color: #008080;">Current cancers can be divided into 2 patient groups as follows:</h2>
<ul>
<li>Group 1 is the most common group nowadays, which is sporadic cancer cases that suddenly occur as individual diseases (Sporadic Case), such as colorectal cancer, lung cancer, liver cancer, etc.</li>
<li>Group 2 is the group of patients with hereditary cancer, caused by changes in certain cells and genes in the body related to cancer development.</li>
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<h2 style="color: #008080;">What can Preventive Genetic Testing detect for hereditary cancer risk (Family of Cancer Syndrome)?</h2>
<ol>
<li>Breast and ovarian cancer Currently, BRCA1 – BRCA2 genes can be tested, which are genes that control cell growth and division. Those who inherit these abnormal genes have a higher chance of developing breast and ovarian cancer.</li>
<li>Colorectal cancer These individuals have abnormal genes inherited genetically. As they age, these abnormal genes cause cells in the colon to change into polyps that can develop into cancer.</li>
<li>Childhood cancers such as eye cancer, caused by gene abnormalities from birth, which is a risk factor for almost all types of childhood cancers.</li>
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<h2 style="color: #008080;">What are the benefits of cancer risk detection using Preventive Genetic Testing?</h2>
Preventive Genetic Testing is a test to detect the risk of cancer by collecting common abnormal cancer genes (Common Cancers) to test individuals who want to be screened.
Early cancer detection using this method can benefit both patients and doctors in monitoring or treating the disease in the future, increasing the chance of complete recovery to nearly 100%. However, sometimes abnormal or suspicious genes may be detected that may not cause cancer in the future, which can affect mental health and family planning preparedness.
<h2 style="color: #008080;">Steps for Preventive Genetic Testing</h2>
Cancer risk detection using Preventive Genetic Testing can be done through blood testing combined with specific reagents to search for abnormal genes in the body or genes that may cause cancer, which are often released and mixed in the blood, called Tumor DNA.
<h2 style="color: #008080;">Who should undergo cancer risk detection with Preventive Genetic Testing?</h2>
<ol>
<li>Those with multiple family members diagnosed with the same type of cancer, such as a grandfather and father with colorectal cancer, increasing the child&#8217;s risk of colorectal cancer.</li>
<li>Those with family members diagnosed with cancer at a young age, such as colorectal cancer under 20 years old, increasing the family&#8217;s risk of colorectal cancer.</li>
<li>Those with family members diagnosed with more than one type of cancer, such as breast cancer followed by ovarian cancer.</li>
<li>Those with family members diagnosed with cancer in paired organs, such as breast cancer or kidney cancer occurring simultaneously on both sides. Normally, cancer occurs in one place and then spreads to other organs, but if it occurs on both sides at the same time, it is suspected to be due to genetic abnormalities.</li>
<li>Those with family members diagnosed with rare cancers, such as soft tissue cancer in children or leukemia combined with eye cancer. Doctors need to provide counseling to other family members of the patient.</li>
<li>Heavy smokers for more than 30 years and those with family members who smoke, as this group has a higher risk of certain cancers, such as lung cancer, bladder cancer, esophageal cancer, and head and neck cancers.</li>
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Dr. Wichit Aphonwirat 
Oncology Specialist 
Cancer Center, Phyathai 2 Hospital

Genetic cancer, although rare, can have its risk detected in advance through Preventive Genetic Testing.

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Detect cancer risk with Preventive Genetic testing for early treatment.

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