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<p>From numerous studies and research, it has been found that 10% of colorectal cancer cases are caused by genetic inheritance. That is, if someone in the family has a history of colorectal cancer, we immediately have a higher risk than the general population. Importantly, colorectal cancer does not only occur in the elderly, so screening should be done regularly from a young age if there is a risk.</p>
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<h2><span style="color: #00826a;">What symptoms should raise suspicion that it might be colorectal cancer?</span></h2>
<p>Dr. Obchula Trachu, a consultant in medical genetics and molecular medicine, Department of Internal Medicine, Phyathai 2 Hospital, explains that the early symptoms of colorectal cancer that can be observed are “patients often experience alternating constipation and diarrhea, pale complexion, fatigue, some may have bloody stools, or a palpable mass in the abdomen.” Therefore, anyone with these symptoms should see a doctor promptly.</p>
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<h2><span style="color: #00826a;">What are the causes of colorectal cancer?<strong><br />
</strong></span></h2>
<p>When the genetics or genes that control the growth of intestinal cells malfunction, normally the intestinal lining cells maintain a balance between cell growth and the destruction of old cells that die. This abnormality may be caused by the accumulation of toxins, radiation, certain medications, or other factors, leading to genetic mutations and an inability to maintain this balance properly. When intestinal cells lose this balance, there is a chance they will grow into tumors and eventually may become cancerous. Another cause that should not be overlooked is a diet low in fiber, eating charred grilled foods, or frequent constipation causing regular irritation to the intestines. These behaviors can stimulate mutations in the intestines.</p>
<h2><span style="color: #00826a;">Age is not always the determinant of colorectal cancer occurrence<strong><br />
</strong></span></h2>
<p>Although colorectal cancer is commonly found in people aged 50 and over in our country, in cases where the cancer is inherited genetically, patients may start showing symptoms at a young age. Some may begin to have symptoms as early as 20 years old. Therefore, whenever there is even one person in the family with colorectal cancer, the others should promptly get tested to assess their risk. This allows for timely screening and treatment because, as mentioned, detecting colorectal cancer early can lead to a complete cure.</p>
<h2><span style="color: #00826a;">When do you fall into the “high-risk group” for colorectal cancer?</span></h2>
<ul>
<li>Having a direct relative such as a father, mother, or sibling diagnosed with colorectal cancer before the age of 45, even just one person</li>
<li>Direct relatives diagnosed with colorectal cancer before the age of 60, even just two people</li>
<li>Other family members including grandparents, uncles, aunts, or cousins diagnosed with colorectal cancer in three or more people, regardless of age</li>
<li>Family members diagnosed with colorectal cancer along with other cancers such as pancreatic cancer, small intestine cancer, stomach cancer, brain cancer, or ovarian cancer in multiple people</li>
</ul>


10% of people with colorectal cancer have it due to genetic inheritance, meaning having a family history of colorectal cancer. Therefore, screening should be done promptly if there is a family member with colorectal cancer.

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Colon cancer: A hereditary disease that can be cured, you just need to recognize it early.

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